Pathology · single question

Which test is used for Sjögren's syndrome?

  1. SSA (anti-Ro antibody) — along with anti-SSB, Schirmer test, minor salivary gland biopsy
  2. ANA only
  3. Rheumatoid factor only
  4. ESR only
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Correct answer: A. SSA (anti-Ro antibody) — along with anti-SSB, Schirmer test, minor salivary gland biopsy

  • A. Correct. Anti-SSA (Ro) antibody testing, along with anti-SSB (La), the Schirmer test, and minor salivary gland (lip) biopsy, are the standard diagnostic tests for Sjögren's syndrome.
  • B. ANA can be positive in Sjögren's but is nonspecific (positive in many autoimmune conditions) and not the specific diagnostic test highlighted.
  • C. Rheumatoid factor can be positive in Sjögren's but is nonspecific and not the specific diagnostic test highlighted.
  • D. ESR is a nonspecific marker of inflammation, not a specific diagnostic test for Sjögren's.

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