Biostatistics & Research · single question
Which study design best minimizes bias in clinical research?
Show answer and explanation
Correct answer: D. Randomized controlled trial
- A. Case-control studies are retrospective and prone to recall/selection bias.
- B. Cohort studies are stronger but still observational and subject to confounding.
- C. Cross-sectional studies capture a snapshot and cannot establish causation.
- D. Correct. The RCT, with randomization and (ideally) blinding, best minimizes bias and is the gold standard for causal inference.
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