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Pharmacology · single question

Which statement about NSAIDs is TRUE?

  1. NSAIDs have a ceiling effect for analgesia
  2. NSAIDs work by activating opioid receptors
  3. NSAIDs are ideal for severe chronic pain as monotherapy
  4. NSAID doses can be increased indefinitely for more pain relief
Show answer and explanation

Correct answer: A. NSAIDs have a ceiling effect for analgesia

NSAIDs have a CEILING EFFECT — beyond maximum therapeutic dose, more drug = more side effects, not more analgesia. They are for mild-moderate pain. They work by inhibiting COX-1/COX-2 enzymes, not opioid receptors.

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