Pharmacology · patient case question

What is the mechanism of action of albuterol?

Patient case: Bone biology and drug mechanisms

Scenario: One histology item followed by a run of mechanism-of-action questions.

  1. Beta-1 adrenergic blocker
  2. Beta-2 adrenergic agonist
  3. Muscarinic antagonist
  4. Leukotriene receptor antagonist
Show answer and explanation

Correct answer: B. Beta-2 adrenergic agonist

  • A. A beta-1 blocker slows the heart and lowers contractility; blocking beta receptors would worsen bronchospasm, not relieve it.
  • B. Correct. Albuterol is a short-acting selective beta-2 agonist. Stimulating beta-2 receptors on bronchial smooth muscle raises cyclic AMP and relaxes the airway — the rescue inhaler in asthma.
  • C. Muscarinic antagonists such as ipratropium do bronchodilate, but by a different route, and albuterol is not one of them.
  • D. Leukotriene antagonists such as montelukast are controller medications taken orally, not rescue bronchodilators.

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