Micro & Immunology · single question
Which organism is intrinsically resistant to clindamycin, making it a poor empiric choice when this organism is suspected?
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Correct answer: A. Pseudomonas aeruginosa
Pseudomonas aeruginosa is intrinsically resistant to clindamycin — clindamycin's clinical spectrum (gram-positive cocci and most anaerobes) doesn't reliably cover gram-negative aerobic rods like Pseudomonas.
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