Micro & Immunology · single question

What is the main function of IgA?

  1. Antibacterial (partial)
  2. Antiviral (prevents mucosal attachment — first line of defense)
  3. Complement activation
  4. Allergic response
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Correct answer: B. Antiviral (prevents mucosal attachment — first line of defense)

  • A. While IgA has some antibacterial activity, its primary highlighted function in this context is antiviral mucosal protection.
  • B. Correct. IgA's main function is to prevent pathogen (especially viral) attachment/adhesion to mucosal surfaces, serving as a first line of mucosal defense.
  • C. IgA is a relatively weak activator of complement compared to IgM and IgG; complement activation is not its main highlighted function.
  • D. Allergic responses are mediated primarily by IgE, not IgA.

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