Micro & Immunology · patient case question

How is the microbiological picture in this condition best characterized?

Patient case: Rapid attachment loss in a young adult

Patient: 26-year-old patient.

Chief complaint: Gums bleed and some teeth feel loose.

History: Non-smoker, no systemic disease. A sibling lost teeth young.

Findings: Radiographs show bone loss disproportionate to the visible plaque, with only light calculus on posterior teeth. Perio charting shows 4 to 5 mm pockets on almost all teeth with bleeding on probing. Clinically, heavy calculus is present on the anterior teeth. Working diagnosis: aggressive (Grade C) periodontitis.

  1. Two strictly aerobic species
  2. Three or more strictly anaerobic species
  3. A single facultative species acting alone
  4. A single strictly anaerobic species
Show answer and explanation

Correct answer: B. Three or more strictly anaerobic species

  • A. Deep pockets are anaerobic environments. Strict aerobes cannot survive there.
  • B. CORRECT. The subgingival flora in aggressive periodontitis is POLYMICROBIAL and dominated by strict anaerobes — Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia and Treponema denticola — alongside Aggregatibacter actinomycetemcomitans. No single organism accounts for the disease.
  • C. A. actinomycetemcomitans is strongly associated with localized aggressive periodontitis, but it acts within a polymicrobial community rather than alone.
  • D. Periodontal disease is not a monomicrobial infection. Isolating one species does not explain the destruction.

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