Pathology · single question

Which of the following is the treatment for Burning Mouth Syndrome (BMS)?

  1. Benzocaine topical
  2. Nortriptyline (tricyclic antidepressant)
  3. Clonazepam topical
  4. Lidocaine topical
Show answer and explanation

Correct answer: B. Nortriptyline (tricyclic antidepressant)

  • A. INCORRECT — Benzocaine is a topical anesthetic without therapeutic benefit for the chronic neuropathic pain of BMS.
  • B. CORRECT — Nortriptyline (a tricyclic antidepressant) is used for chronic neuropathic pain management in BMS. TCAs modulate central pain processing pathways. Other evidence-based treatments include clonazepam (topical), capsaicin, and alpha-lipoic acid.
  • C. INCORRECT — Clonazepam topical (swish and spit) is also an evidence-based option for BMS, but nortriptyline (systemic TCA) is the more classic INBDE answer. Both are valid; source notes both.
  • D. INCORRECT — Topical lidocaine provides temporary anesthetic relief but is not a long-term treatment for BMS and does not address the neuropathic mechanism.

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