Pathology · single question
Which of the following is NOT a differential diagnosis for irritation fibroma?
Show answer and explanation
Correct answer: C. Lichen planus (oral)
C) Lichen planus — CORRECT (NOT a differential for irritation fibroma).
Irritation fibroma is a localized fibrous hyperplasia from chronic trauma. Differential diagnoses include other reactive/hyperplastic lesions: peripheral ossifying fibroma, peripheral giant cell granuloma, pyogenic granuloma, and epulis fissuratum. Lichen planus is a mucosal immune-mediated condition presenting as white striae (Wickham's striae), erosions, or bullae — a completely different pathological entity from fibroma.
A) Peripheral giant cell granuloma: Reactive lesion — valid differential.
B) Leukoplakia: A white patch that could overlap clinically — valid differential to consider.
D) Pyogenic granuloma: Reactive vascular lesion — valid differential.
Irritation fibroma is a localized fibrous hyperplasia from chronic trauma. Differential diagnoses include other reactive/hyperplastic lesions: peripheral ossifying fibroma, peripheral giant cell granuloma, pyogenic granuloma, and epulis fissuratum. Lichen planus is a mucosal immune-mediated condition presenting as white striae (Wickham's striae), erosions, or bullae — a completely different pathological entity from fibroma.
A) Peripheral giant cell granuloma: Reactive lesion — valid differential.
B) Leukoplakia: A white patch that could overlap clinically — valid differential to consider.
D) Pyogenic granuloma: Reactive vascular lesion — valid differential.