Pathology · single question

What type of hypersensitivity reaction is allergic contact dermatitis?

  1. Type IV
  2. Type I
  3. Type II
  4. Type III
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Correct answer: A. Type IV

Allergic contact dermatitis is a Type IV (delayed-type, T-cell/cell-mediated) hypersensitivity reaction, developing over 24-72 hours after re-exposure to a sensitizing allergen. This differs from irritant contact dermatitis, which is a non-immunologic reaction caused by direct chemical/physical irritation or friction, not an allergic mechanism at all.

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