Implants · single question
Which of the following does NOT favor osteoinduction?
Show answer and explanation
Correct answer: C. Interleukin-1 (IL-1)
IL-1 (Interleukin-1) is a pro-inflammatory cytokine that promotes bone resorption (stimulates osteoclasts) and does NOT favor osteoinduction.
- A. ❌ Extracellular matrix components provide the scaffold for osteoinduction.
- B. ❌ MMPs participate in bone remodeling and create space for new bone.
- C. ✅ CORRECT – IL-1 is pro-resorptive; it does NOT favor osteoinduction.
- D. ❌ Growth factors (BMP, PDGF, TGF-β) PROMOTE osteoinduction by stimulating osteoblast differentiation.