Micro & Immunology · single question

Which immunoglobulin mediates type I (immediate) hypersensitivity such as anaphylaxis?

  1. IgG
  2. IgM
  3. IgE
  4. IgA
Show answer and explanation

Correct answer: C. IgE

  • A. IgG mediates type II/III reactions, not classic immediate hypersensitivity.
  • B. IgM is the first antibody in a primary response.
  • C. Correct. IgE binds mast cells/basophils and triggers type I hypersensitivity.
  • D. IgA is the secretory/mucosal antibody.

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