Pathology · single question

Which clinical sign is characteristic of pemphigus vulgaris?

  1. Positive Nikolsky sign
  2. Auspitz sign
  3. Koplik spots
  4. Wickham striae
Show answer and explanation

Correct answer: A. Positive Nikolsky sign

  • A. Correct. A positive Nikolsky sign (epithelium sloughs with lateral pressure) reflects the intraepithelial acantholysis of pemphigus.
  • B. Incorrect. The Auspitz sign (pinpoint bleeding after scale removal) is seen in psoriasis.
  • C. Incorrect. Koplik spots are pathognomonic for measles.
  • D. Incorrect. Wickham striae (fine white lines) are seen in lichen planus.

Practice Pathology questions Pathology study notes

More Pathology practice questions