Micro & Immunology · single question

Which bacteria does clindamycin target?

  1. Gram-positive anaerobes (NOT Pseudomonas aeruginosa)
  2. Gram-negative aerobes
  3. All gram-negative organisms
  4. Pseudomonas aeruginosa
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Correct answer: A. Gram-positive anaerobes (NOT Pseudomonas aeruginosa)

CLINDAMYCIN covers: GRAM-POSITIVE cocci (Staph, Strep), GRAM-NEGATIVE ANAEROBES (Bacteroides species), and GRAM-POSITIVE ANAEROBES. It is EXCELLENT for ANAEROBIC infections. It does NOT cover GRAM-NEGATIVE AEROBES and is notably INEFFECTIVE against PSEUDOMONAS AERUGINOSA and Enterococcus. In dentistry, clindamycin is used as an alternative antibiotic prophylaxis (penicillin-allergic) and for odontogenic infections with mixed anaerobes. A is correct.

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