Pathology · patient case question

What is the tissue lesion at the denture border?

Patient case: Case: something under the denture

Scenario: A denture wearer reports feeling something beneath the prosthesis and is worried it may be malignant. On examination the palate is diffusely red beneath the denture, and there is a folded, fibrous overgrowth of tissue at the denture border. Four linked questions followed.

  1. Squamous cell carcinoma
  2. Epulis fissuratum
  3. Peripheral giant cell granuloma
  4. Fibroma
Show answer and explanation

Correct answer: B. Epulis fissuratum

  • A. Carcinoma would be indurated and ulcerated with rolled borders, and would not conform so neatly to the flange outline. The patient's fear is reasonable but the clinical picture is reassuring.
  • B. Correct. Epulis fissuratum is a reactive hyperplasia of fibrous connective tissue produced by a chronically overextended or ill-fitting denture flange. The classic sign is folds of tissue with the flange sitting in the fissure between them.
  • C. A peripheral giant cell granuloma is a purple-red gingival mass arising from the periodontal ligament or periosteum, typically in dentate areas, and can resorb underlying bone.
  • D. A fibroma is a discrete, smooth, dome-shaped nodule from focal trauma — not a folded overgrowth along a denture border.

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