Pathology · single question

Besides dry skin and missing teeth, what additional finding might you expect in a patient with hypohidrotic ectodermal dysplasia?

  1. Dry eyes (reduced lacrimal gland secretion, part of broader exocrine gland hypofunction)
  2. Excessive tearing
  3. Excessive salivation
  4. Hyperhidrosis (excessive sweating)
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Correct answer: A. Dry eyes (reduced lacrimal gland secretion, part of broader exocrine gland hypofunction)

Hypohidrotic ectodermal dysplasia can affect multiple exocrine glands beyond sweat glands, including the lacrimal glands, leading to dry eyes — consistent with the broader pattern of reduced exocrine gland function (hypohidrosis, xerostomia in some cases, and dry eyes) seen in this condition.

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