Medical Emergencies · patient case question

What is the most appropriate immediate drug intervention?

Patient case: Medical Emergency in the Operatory

demo: 34-year-old female

chief: Composite restoration on tooth #3 under rubber dam isolation.

history: Asthma, well controlled. No known drug allergies. Latex sensitivity not previously documented.

meds: Albuterol inhaler as needed

findings: Ten minutes after rubber dam placement the patient develops audible wheezing, swelling of the lips and periorbital tissue, and urticaria over the neck.

  1. Diphenhydramine 50 mg orally
  2. Hydrocortisone 100 mg intravenously
  3. Epinephrine 1:1000, 0.3 mg intramuscularly
  4. Albuterol inhaler, 2 puffs
Show answer and explanation

Correct answer: C. Epinephrine 1:1000, 0.3 mg intramuscularly

  • A. Antihistamines are adjunctive and far too slow for airway compromise; they treat the cutaneous signs only.
  • B. Corticosteroids blunt the late-phase reaction but have no useful onset in the first minutes.
  • C. Correct. Wheezing plus angioedema and urticaria is anaphylaxis. Intramuscular epinephrine 1:1000 is the first-line drug — remove the dam, position the patient, give oxygen, and activate EMS.
  • D. Albuterol addresses bronchospasm but does nothing for the angioedema or the circulatory component.

Note: Sequence matters: remove the allergen, epinephrine first, then oxygen, call 911, and give antihistamine and corticosteroid as secondary agents.

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