Medical Emergencies · single question
Sjögren's Syndrome is associated with which systemic condition?
Show answer and explanation
Correct answer: D. Both SLE and Rheumatoid Arthritis
Both SLE and Rheumatoid Arthritis (D) — Sjögren's Syndrome (SS) is associated with multiple autoimmune conditions. Secondary Sjögren's occurs in the context of another autoimmune disease — most commonly:
• Rheumatoid Arthritis (most common association)
• Systemic Lupus Erythematosus (SLE)
• Scleroderma, Primary Biliary Cirrhosis, Polymyositis
• Primary Sjögren's: SS without another CTD.
• Triad: xerostomia (dry mouth), xerophthalmia (dry eyes), and systemic autoimmune features.
• Anti-SSA (Ro) and Anti-SSB (La) antibodies are diagnostic markers.
• Increased risk of MALT lymphoma (major concern in SS patients).
• Dental management: saliva substitutes, fluoride supplements, frequent caries prevention, treat xerostomia.
• Rheumatoid Arthritis (most common association)
• Systemic Lupus Erythematosus (SLE)
• Scleroderma, Primary Biliary Cirrhosis, Polymyositis
• Primary Sjögren's: SS without another CTD.
• Triad: xerostomia (dry mouth), xerophthalmia (dry eyes), and systemic autoimmune features.
• Anti-SSA (Ro) and Anti-SSB (La) antibodies are diagnostic markers.
• Increased risk of MALT lymphoma (major concern in SS patients).
• Dental management: saliva substitutes, fluoride supplements, frequent caries prevention, treat xerostomia.
Practice Medical Emergencies questions Medical Emergencies study notes