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Pharmacology · single question

The same patient (Type I hypersensitivity from anesthesia) develops hives. What is the management of the hives?

  1. Topical or systemic antihistamines
  2. Corticosteroids IV only
  3. No treatment needed — they resolve spontaneously
  4. Epinephrine IM only
Show answer and explanation

Correct answer: A. Topical or systemic antihistamines

  • A. Correct. Hives (urticaria) from Type I hypersensitivity are managed with antihistamines (H1-blockers like diphenhydramine/Benadryl). Topical antihistamines help localized mild hives; systemic antihistamines (oral or IV) are used for widespread urticaria. If anaphylaxis progresses, epinephrine is the primary treatment, but hives alone are managed with antihistamines.
  • B. Corticosteroids IV help reduce delayed inflammatory response but are secondary to antihistamines for hives.
  • C. Hives can persist and cause discomfort — active management with antihistamines is appropriate.
  • D. Epinephrine IM is the treatment for anaphylaxis/severe allergic reaction — not for hives alone.

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