Pathology · single question

What is the gold standard diagnostic test for obstructive sleep apnea (OSA)?

  1. Epworth Sleepiness Scale questionnaire
  2. Overnight pulse oximetry
  3. Overnight polysomnography (PSG/sleep study)
  4. Lateral cephalometric radiograph
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Correct answer: C. Overnight polysomnography (PSG/sleep study)

Overnight polysomnography (PSG) is the gold standard for diagnosing OSA. It simultaneously measures: EEG (brain activity/sleep stages), respiratory airflow, oxygen saturation, chest/abdominal movement, and heart rate. The AHI (apnea-hypopnea index) derived from PSG classifies OSA severity.
  • A. ❌ Epworth Sleepiness Scale screens for daytime sleepiness but does not diagnose OSA.
  • B. ❌ Pulse oximetry shows O2 desaturations but is not the comprehensive gold standard.
  • C. ✅ Overnight polysomnography — the gold standard; measures all parameters needed for OSA diagnosis and severity.
  • D. ❌ Cephalometric radiograph can identify anatomical risk factors but does not diagnose OSA.

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