Pathology · single question

Which tissue is NOT affected by ectodermal dysplasia?

  1. Oral mucosa
  2. Salivary glands
  3. Hair follicles
  4. Blood vessels
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Correct answer: D. Blood vessels

  • A. Oral mucosal epithelium is ectodermal and is affected — it is often dry and atrophic.
  • B. Salivary glands are ectodermally derived — their hypoplasia causes the xerostomia seen in these patients.
  • C. Hair follicles are ectodermal — hypotrichosis (sparse, fine hair) is a cardinal feature, along with hypodontia/anodontia, hypohidrosis, and dysplastic nails.
  • D. Correct (NOT affected). BLOOD VESSELS are MESODERMAL in origin. Ectodermal dysplasia is a defect of structures derived from ECTODERM, so vascular tissue is spared.

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