Pharmacology · single question

What analgesic is most appropriate for a patient with a history of gastric ulcer needing post-extraction pain relief?

  1. Benzocaine topical (Orajel)
  2. Ibuprofen (Motrin)
  3. Aspirin/Paracetamol (Excedrin)
  4. Celecoxib (Celebrex)
Show answer and explanation

Correct answer: D. Celecoxib (Celebrex)

Celecoxib selectively inhibits COX-2 (inflammation) while sparing COX-1 (gastric mucosal protection), making it safe for patients with GI disease. Ibuprofen and aspirin are non-selective COX inhibitors that damage the gastric mucosa. Benzocaine is a topical anesthetic, not analgesic.

Practice Pharmacology questions Pharmacology study notes

More Pharmacology practice questions