Medical Emergencies · single question

The same child receiving chemotherapy is at greatest risk of which complication following dental treatment?

  1. Infection
  2. Malignant hyperthermia
  3. Ankylosis of the extraction site
  4. Osteoradionecrosis
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Correct answer: A. Infection

  • A. ✅ CORRECT — Chemotherapy-induced MYELOSUPPRESSION causes neutropenia, and a neutropenic child cannot mount a normal inflammatory response. Odontogenic infection can progress rapidly to bacteremia and sepsis. Mucositis compounds the problem by breaching the mucosal barrier.
  • B. ❌ Malignant hyperthermia is a pharmacogenetic reaction to volatile anesthetics and succinylcholine, unrelated to chemotherapy.
  • C. ❌ Ankylosis follows traumatic injury with replacement resorption; it is not a chemotherapy complication.
  • D. ❌ Osteoradionecrosis follows RADIATION to the jaws, not chemotherapy.

Note: Also expect: mucositis, xerostomia, spontaneous gingival bleeding from thrombocytopenia, candidiasis and herpetic reactivation.

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