Medical Emergencies · single question

When a patient with hemophilia requires a dental procedure, which laboratory test is MOST important to check?

  1. PT (prothrombin time)
  2. PTT (partial thromboplastin time)
  3. INR
  4. Platelet count
Show answer and explanation

Correct answer: B. PTT (partial thromboplastin time)

  • A. PT measures the extrinsic pathway (factors VII, X, V, II, fibrinogen) — normal in hemophilia.
  • B. Correct. Hemophilia A (Factor VIII deficiency) and Hemophilia B (Factor IX deficiency) are intrinsic pathway defects. The PTT (partial thromboplastin time) measures the intrinsic and common pathways and will be PROLONGED in hemophilia. PT/INR are typically NORMAL.
  • C. INR is derived from PT — normal in hemophilia; used for monitoring warfarin therapy.
  • D. Platelet count is normal in hemophilia — platelets are not affected; it is the clotting factor that is deficient.

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