Pathology · single question

The most frequent location of RECURRENT herpes simplex (herpes labialis) is:

  1. Dorsum of the tongue
  2. Attached gingiva
  3. Mucocutaneous junction (vermilion border) of the lip
  4. Floor of the mouth
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Correct answer: C. Mucocutaneous junction (vermilion border) of the lip

  • A. The tongue dorsum is not the typical site of recurrent HSV.
  • B. Attached/keratinized gingiva and hard palate are sites for recurrent INTRAORAL HSV, but the most common overall recurrence is herpes labialis.
  • C. Correct. Recurrent HSV most commonly presents as herpes labialis at the mucocutaneous (vermilion) junction of the lips.
  • D. The floor of the mouth (non-keratinized) is not a typical recurrence site.

Note: Recurrent INTRAORAL herpes favors keratinized mucosa (attached gingiva, hard palate); recurrent herpes overall (labialis) favors the vermilion border.

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