Pathology · single question

Ectodermal dysplasia affects structures derived from ectoderm. Which of the following is the EXCEPTION — i.e., NOT typically affected?

  1. Skin
  2. Sweat glands
  3. Adrenal glands
  4. Hair and teeth
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Correct answer: C. Adrenal glands

Ectodermal dysplasia is a group of inherited disorders affecting ectoderm-derived structures: skin, hair, nails, sweat glands, and teeth (commonly causing hypodontia/anodontia and peg-shaped teeth). The adrenal glands, derived from a combination of mesoderm (cortex) and neural crest/ectoderm (medulla) but not classically implicated in this syndrome's defect, are not typically affected.

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