Pathology · single question
Sjögren's syndrome is associated with which of the following systemic conditions?
Show answer and explanation
Correct answer: A. Lupus erythematosus (SLE)
- A. Sjögren's syndrome is strongly associated with SYSTEMIC LUPUS ERYTHEMATOSUS (SLE). Secondary Sjögren's syndrome (sicca syndrome in the context of another autoimmune disease) is commonly associated with SLE, rheumatoid arthritis, and scleroderma. SSA/Ro and SSB/La antibodies cross over with lupus.
- B. Crohn's has inflammatory features but is not the primary systemic association tested for Sjögren's syndrome.
- C. T2DM is a metabolic disease — not the classic autoimmune association for Sjögren's.
- D. Hypertension is not an autoimmune association of Sjögren's.