Pathology · single question

A heavy pipe smoker presents with diffuse whitening of the hard palate with red dot-like openings of minor salivary gland ducts. What is the most likely diagnosis?

  1. Nicotinic stomatitis (smoker's palate)
  2. Candidiasis
  3. Leukoplakia
  4. Erythroplakia
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Correct answer: A. Nicotinic stomatitis (smoker's palate)

Nicotinic stomatitis (stomatitis nicotina) is a benign reactive change of the hard palate associated with tobacco smoking, particularly pipe and cigar smoking. It presents as diffuse whitening (hyperkeratosis) of the hard palate with characteristic red dots representing inflamed and dilated minor salivary gland duct orifices. Despite its dramatic appearance, nicotinic stomatitis carries a low malignant potential — it is a reactive hyperkeratosis, not a dysplasia. The condition typically resolves when smoking is discontinued. It is important to differentiate from leukoplakia of the palate in reverse smokers (where the lit end is held in the mouth), which carries significant malignant potential.

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