Pathology · single question

Rheumatoid Arthritis is related to all of the following EXCEPT:

  1. Stress areas caused by weight bearing
  2. Infection
  3. TMJ problems
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Correct answer: A. Stress areas caused by weight bearing

✓ A) Stress caused by weight bearing is the EXCEPTION.
Rheumatoid arthritis is an autoimmune/inflammatory condition, not a wear-and-tear/mechanical disease. Osteoarthritis is the weight-bearing/mechanical joint disease. RA is triggered by autoimmune mechanisms (possibly with infectious triggers), and it does affect the TMJ (bilateral involvement, condylar destruction).
  • A. Infection IS associated with RA — certain infections (e.g., P. gingivalis) are linked to triggering or worsening RA. This IS a true association.
  • B. Rheumatoid arthritis (RA) is an AUTOIMMUNE condition affecting synovial joints — it is NOT caused by mechanical stress from weight bearing. Unlike osteoarthritis (which IS related to mechanical stress/wear), RA is driven by autoimmune inflammation targeting synovial membranes. This is the exception.
  • C. Symmetrical joint involvement IS a hallmark of RA (distinguishing it from other arthritides). This IS true of RA.

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