Pharmacology · single question
Same patient with asthma reports that aspirin triggers wheezing. Which medication is most appropriate for pain management?
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Correct answer: C. Acetaminophen
- A. Ibuprofen is an NSAID; in aspirin-exacerbated respiratory disease, NSAIDs can cross-react and precipitate bronchospasm.
- B. Naproxen is also an NSAID and carries the same cross-reactivity risk.
- C. Correct. Acetaminophen is not a COX-1 inhibitor in the relevant pathway and is the safe analgesic choice in aspirin-sensitive asthma.
- D. Etodolac is still an NSAID; despite COX-2 preference it is generally avoided in aspirin-sensitive asthmatics as the safest option.