Pharmacology · single question

Pemphigus vulgaris — what is the treatment?

  1. Antifungals
  2. Antibiotics
  3. Systemic corticosteroids
  4. Antivirals
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Correct answer: A. Antifungals

  • A. Correct. Systemic corticosteroids (prednisone) are the mainstay of treatment for pemphigus vulgaris, targeting the autoimmune IgG-mediated acantholysis of desmoglein.
  • B. Incorrect. Antifungals treat fungal infections; pemphigus is autoimmune.
  • C. Incorrect. Antivirals are not indicated unless concurrent herpetic infection is present.
  • D. Incorrect. Antibiotics treat bacterial infections, not autoimmune bullous disease.

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