Pharmacology · single question

What is the half-life of methamphetamine when administered intravenously?

  1. 16-20 hours
  2. 24-36 hours
  3. 3-5 hours
  4. 9-12 hours
Show answer and explanation

Correct answer: D. 9-12 hours

  • A. 16-20 hours overestimates the methamphetamine half-life.
  • B. 24-36 hours is far too long — this would apply to drugs like amiodarone.
  • C. 3-5 hours is too short for methamphetamine's half-life.
  • D. Correct. Methamphetamine has a half-life of approximately 9-12 hours (IV route). Oral and intranasal routes have similar half-lives (~9h). Smoked routes are slightly longer (~12h). This long half-life contributes to its prolonged stimulant effects.

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