Pathology · single question

Most common location of recurrent herpes simplex (intraoral recurrence):

  1. Attached gingiva (and hard palate)
  2. Buccal mucosa
  3. Floor of mouth
  4. Soft palate
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Correct answer: A. Attached gingiva (and hard palate)

  • A. Correct. Intraoral recurrent HSV lesions classically occur on keratinized tissue — the attached gingiva and hard palate — distinguishing them from herpetiform aphthous ulcers, which occur on non-keratinized mucosa.
  • B. Buccal mucosa is non-keratinized and is the more typical site for aphthous ulcers, not recurrent intraoral herpes.
  • C. Floor of mouth is non-keratinized tissue, atypical for recurrent intraoral HSV.
  • D. Soft palate is non-keratinized tissue, atypical for recurrent intraoral HSV (primary HSV can involve broader mucosa, but RECURRENT lesions favor keratinized tissue).

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