Pathology · single question

A 25-year-old patient presents with a firm, non-tender 1 cm elevated lesion on the buccal mucosa with a central 1 cm ulceration on its surface. The MOST likely diagnosis is:

  1. Fibroma
  2. Ranula
  3. Mucocele
  4. Nodule
Show answer and explanation

Correct answer: D. Nodule

A nodule is a solid elevated lesion >5mm in diameter. When a nodule has surface ulceration (as described here), it warrants biopsy to rule out malignancy. The clinical description — firm, elevated, non-tender buccal lesion with central ulceration — is classic for a nodule. Management: incisional biopsy to establish diagnosis.
  • A. ❌ A fibroma is typically firm and sessile/pedunculated but does not characteristically present with central ulceration.
  • B. ❌ A ranula is a large mucocele on the floor of the mouth with a characteristic bluish, fluctuant appearance.
  • C. ❌ A mucocele is fluid-filled, fluctuant, and bluish — not firm with ulceration.
  • D. ✅ CORRECT – A nodule is a solid elevated lesion >5mm. Central ulceration on a nodule raises concern and warrants incisional biopsy.

Practice Pathology questions Pathology study notes

More Pathology practice questions