Physiology & Biochemistry · single question

In Duchenne muscular dystrophy (X-linked recessive), the mother is a carrier and the father is unaffected. What percentage of their daughters will be carriers?

  1. 25%
  2. 50%
  3. 75%
  4. 100%
Show answer and explanation

Correct answer: B. 50%

The carrier mother is heterozygous (Xx); the unaffected father contributes a normal X to all daughters. Each daughter has a 50% chance of inheriting the affected X from her carrier mother (making her a carrier, Xx) and a 50% chance of inheriting the normal X (making her unaffected, XX) — so 50% of daughters are expected to be carriers.

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