Physiology & Biochemistry · single question

Both xylitol and arginine have anticariogenic properties. Which statement is TRUE?

  1. Xylitol inhibits S. mutans; arginine raises plaque pH via ammonia production
  2. Arginine is fermentable and lowers pH
  3. Xylitol raises pH via ammonia; arginine is a sugar substitute
  4. Both are fermentable sugars
Show answer and explanation

Correct answer: A. Xylitol inhibits S. mutans; arginine raises plaque pH via ammonia production

  • A. Correct. Xylitol is a non-fermentable sugar alcohol that inhibits S. mutans metabolism/growth, while arginine is metabolized to ammonia, raising/buffering plaque pH — two distinct anticariogenic mechanisms.
  • B. Arginine is NOT fermentable into acid and does not lower pH — it raises pH via ammonia production, the opposite of this statement.
  • C. This swaps the mechanisms — xylitol does not work via ammonia production, and arginine is not simply a 'sugar substitute' in the way xylitol is.
  • D. Neither is a fermentable sugar in the cariogenic sense — xylitol is non-fermentable by cariogenic bacteria, and arginine is an amino acid, not a sugar.

Note: Memory trick: 'Arginine = Alkaline' | 'Xylitol = eXterminates mutans.'

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