Pathology · single question
In an HIV-positive patient, a lesion shows elongated rete pegs on histology. Most likely diagnosis?
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Correct answer: B. Kaposi's sarcoma
Kaposi's sarcoma (HHV-8) in HIV patients: spindle cells, abnormal vascular channels, can show elongated rete pegs overlying the lesion. Oral hairy leukoplakia = EBV, lateral tongue, hairy projections.