Biostatistics & Research · single question

In a PICO question about fluoride varnish — what does the 'I' represent?

  1. Intervention (fluoride varnish application)
  2. Incidence of caries
  3. Indication for treatment
  4. Index of fluorosis
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Correct answer: A. Intervention (fluoride varnish application)

✓ A) Intervention is correct.
PICO framework: P = Patient/Population, I = Intervention (the treatment or exposure being studied — in this case, fluoride varnish), C = Comparison (control or alternative treatment), O = Outcome. Fluoride varnish is the intervention being evaluated. PICO is the standard framework for formulating clinical research questions in evidence-based dentistry.

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