In the PICO framework for evidence-based practice, what does the letter 'I' stand for?

PICO is a framework used to formulate clinical research questions in evidence-based dentistry and medicine. The letters stand for: P = Patient/Population/Problem, I = Intervention (the treatment, diagnostic test, or exposure being studied), C = Comparison (the alternative or control intervention), and O = Outcome (the clinical result of interest). A well-constructed PICO question helps clinicians efficiently search the literature and critically appraise evidence to guide clinical decision-making.