Biostatistics & Research · single question
Which study design provides the HIGHEST level of primary evidence?
Show answer and explanation
Correct answer: C. Randomized controlled trial (RCT)
Evidence hierarchy (primary studies): RCT > Cohort > Case-control > Cross-sectional > Case series > Case report > Expert opinion. Meta-analyses of RCTs sit at the very apex (secondary research). RCT = highest PRIMARY evidence due to randomization minimizing bias.
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