Pharmacology · single question

Humira (adalimumab) works by:

  1. Inhibiting RANKL
  2. Blocking the 5-HT1A receptor
  3. Binding and neutralizing TNF-╬▒
  4. Inhibiting bacterial cell wall synthesis
Show answer and explanation

Correct answer: C. Binding and neutralizing TNF-╬▒

Adalimumab is a fully humanized monoclonal antibody against TNF-╬▒, used for rheumatoid arthritis, psoriasis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, and hidradenitis suppurativa. Because it is immunosuppressive, patients are at increased risk of serious infections (including reactivation of tuberculosis and hepatitis B), and dental infections should be managed aggressively.16. Xerostomia & Cancer Therapy

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