Pharmacology · single question

All of the following antibiotics are BACTERICIDAL EXCEPT one. Which is the exception?

  1. Cephalexin (a cephalosporin)
  2. Amoxicillin (a penicillin)
  3. Penicillin VK
  4. Doxycycline (a tetracycline)
Show answer and explanation

Correct answer: D. Doxycycline (a tetracycline)

Doxycycline is a bacteriostatic antibiotic — it inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing growth and reproduction, but does not directly kill bacteria. Beta-lactams (penicillins, cephalosporins) are bactericidal — they inhibit cell wall synthesis causing bacterial death. Key memory: 'Static' = Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Sulfonamides (mnemonic: STATIC).

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