Periodontics · single question
GTR (Guided Tissue Regeneration) is BEST indicated for which periodontal defect?
Show answer and explanation
Correct answer: B. Class II furcation involvement and 2-3 wall vertical infrabony defects
✓ B) Class II furcation and 2–3 wall vertical defects are the BEST indications for GTR.
GTR uses a barrier membrane (resorbable or non-resorbable) to exclude epithelium and connective tissue, allowing PDL progenitor cells to repopulate the defect → new cementum + PDL + alveolar bone. BEST outcomes with: (1) 2–3 walled vertical infrabony defects (more walls = better blood supply for clot stabilization); (2) Class II mandibular furcation; (3) Narrow, deep defects. POOR outcomes: (1) 1-wall defects (insufficient bone walls); (2) Class III furcation (complete); (3) Horizontal bone loss. Combined with bone grafts: even better results (enamel matrix derivative for regeneration).
GTR uses a barrier membrane (resorbable or non-resorbable) to exclude epithelium and connective tissue, allowing PDL progenitor cells to repopulate the defect → new cementum + PDL + alveolar bone. BEST outcomes with: (1) 2–3 walled vertical infrabony defects (more walls = better blood supply for clot stabilization); (2) Class II mandibular furcation; (3) Narrow, deep defects. POOR outcomes: (1) 1-wall defects (insufficient bone walls); (2) Class III furcation (complete); (3) Horizontal bone loss. Combined with bone grafts: even better results (enamel matrix derivative for regeneration).