Physiology & Biochemistry · single question

Gout results from a disorder in the metabolism of which class of compounds?

  1. Fatty acids
  2. Amino acids
  3. Purines (nucleic acids)
  4. Simple carbohydrates
Show answer and explanation

Correct answer: C. Purines (nucleic acids)

  • A. Incorrect. Fatty acid disorders cause dyslipidemia and hepatic steatosis, not crystal arthropathy.
  • B. Incorrect. Amino acid metabolic disorders include phenylketonuria and maple syrup urine disease.
  • C. Correct. Gout results from hyperuricemia — uric acid is the end product of purine (nucleic acid) catabolism. Monosodium urate crystals deposit in joints, classically the first metatarsophalangeal joint.
  • D. Incorrect. Carbohydrate metabolic disorders include diabetes and galactosemia.

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