Micro & Immunology · single question

Four weeks later the same patient develops target (iris) skin lesions. The diagnosis and hypersensitivity type are:

  1. Erythema multiforme — type IV (delayed) hypersensitivity
  2. Urticaria — type I
  3. Pemphigus — type II
  4. Lupus — type III
Show answer and explanation

Correct answer: A. Erythema multiforme — type IV (delayed) hypersensitivity

  • A. Correct. Target/iris lesions are characteristic of erythema multiforme, a delayed (type IV) cell-mediated hypersensitivity often triggered by drugs or infection.
  • B. Urticaria (type I) produces transient wheals, not fixed target lesions.
  • C. Pemphigus is an autoimmune blistering disease (type II), not target lesions.
  • D. Lupus (type III immune complex) does not present as classic iris targets.

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