Female patient: lethargy, BP 80/60, diffuse bronze skin pigmentation. Diagnosis?

Hypothyroidism
Pheochromocytoma
Addison's disease (primary adrenal insufficiency)
Cushing's syndrome

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Correct answer: C. Addison's disease (primary adrenal insufficiency)

ADDISON'S DISEASE: fatigue, HYPOTENSION, weight loss, BRONZE SKIN HYPERPIGMENTATION (elevated ACTH cross-reacts with melanocortin receptors). Oral: patchy mucosal pigmentation. Lab: low cortisol, high ACTH, hyponatremia, hyperkalemia.

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Female patient: lethargy, BP 80/60, diffuse bronze skin pigmentation. Diagnosis?

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