Pathology · single question

Dentinogenesis imperfecta — opalescent gray-blue teeth with bulbous crowns.

  1. Amelogenesis imperfecta type 1
  2. Amelogenesis imperfecta type 2
  3. Dentinogenesis imperfecta type 2
  4. Dentinogenesis imperfecta type 1 (with osteogenesis imperfecta)
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Correct answer: C. Dentinogenesis imperfecta type 2

DI type II (Shields classification) is an isolated autosomal-dominant dentin disorder caused by DSPP mutations. Classic findings: opalescent gray-blue-brown teeth, bulbous crowns with cervical constriction, obliteration of pulp chambers/canals, and crown fracture due to weak dentin-enamel junction. DI type I is associated with osteogenesis imperfecta; amelogenesis imperfecta primarily affects enamel, not dentin/pulp.

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