Pathology · single question

Same HPV case — which descriptor best characterizes the appearance of the lesion?

  1. Papillary
  2. Ulcerative
  3. Flat
  4. Verrucous
Show answer and explanation

Correct answer: A. Papillary

✓ A) Papillary is correct.
HPV-associated oral lesions (squamous papilloma, condyloma, verruca vulgaris) have a characteristic papillary/exophytic surface — multiple finger-like or cauliflower-like projections of epithelium. This is distinct from ulcerative lesions (aphthous, traumatic ulcers), flat lesions (leukoplakia), or sessile lesions. The papillary architecture on histology shows finger-like epithelial projections supported by fibrovascular cores, which is the hallmark morphology of HPV-induced lesions.

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