DAY 2 — CASE 16: A patient reports experiencing amnesia after receiving a medication during a dental procedure. Which medication is most likely responsible?

Correct answer: C. Midazolam

• A. Triazolam (Halcion) is an oral benzodiazepine used for dental premedication with amnestic effects, but midazolam is more potent and commonly cited.
• B. Diazepam (Valium) can cause some anterograde amnesia but is less potent and shorter-acting for amnesia than midazolam.
• C. MIDAZOLAM (Versed) is the benzodiazepine most strongly associated with ANTEROGRADE AMNESIA in dentistry. It is used specifically for procedural sedation because of its reliable, profound amnestic effect. Patients often have little or no memory of the procedure. It has a rapid onset and is the standard IV/intranasal sedation agent in dental conscious sedation. It is the correct answer for amnesia in a dental sedation context.
• D. Lorazepam also causes amnesia but is less commonly used for dental procedural sedation.