Pharmacology · single question
A patient taking methotrexate and adalimumab (Humira) needs a tooth extraction. What pre-operative test is most appropriate?
Show answer and explanation
Correct answer: A. Complete blood count (CBC)
- A. Correct. Both methotrexate and adalimumab suppress the immune system and can cause bone marrow suppression. A CBC is needed to evaluate white blood cell count and platelet levels before any surgical procedure.
- B. Serum creatinine evaluates kidney function and may be relevant to drug dosing but is not the primary pre-op concern here.
- C. HbA1c is for diabetes monitoring — not relevant to immunosuppressant-related surgical risk.
- D. INR is appropriate for patients on anticoagulants like warfarin, not for immunosuppressants like methotrexate/Humira.